nucleosome
/noo-klee-uh-sohm, nyoo-/US // ˈnu kli əˌsoʊm, ˈnyu- //UK // (ˈnjuːklɪəˌsəʊm) //
核小体,核糖体,核子体,核糖核酸体
Definitions
n.名词 noun
- 1
Cell Biology.
- : any of the repeating subunits of chromatin occurring at intervals along a strand of DNA, consisting of DNA coiled around histone.
Examples
As a first step toward those answers, Sandman joined forces several years ago with the structural biologist Karolin Luger, who solved the structure of the eukaryotic nucleosome in 1997.
Together, they worked out the crystallized structure of the archaeal nucleosome, which they published with colleagues in 2017.
By curving the DNA around the nucleosome, the histones prevent it from clumping together and keep it functional.
Last July, Kurdistani’s team reported that in yeast nucleosomes, there is a catalytic site at the interface of two histone H3 proteins that can bind and electrochemically reduce copper.
By wrapping the DNA, the nucleosomes keep the DNA safely out of the way.
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