Biochemistry. an estrogenic hormone, C18H24O2, produced by the maturing Graafian follicle, that causes proliferation and thickening of the tissues and blood vessels of the endometrium.
Pharmacology. a commercial form of this compound, obtained from the urine of pregnant humans and mares or synthesized, used in the treatment of estrogen deficiency and certain menopausal and postmenopausal conditions.
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In women, there did seem to be a link between low levels of testosterone and estradiol and low bone mineral density.